Piperidine → 1-Piperidinesulfonamide

HRID 424687

反応式

HRID 424687 の反応式
[NH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[S:7](N)([NH2:10])(=[O:9])=[O:8]>O1CCOCC1>[N:1]1([S:7]([NH2:10])(=[O:9])=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

参加物

4

反応物 2

HCID 8082PiperidineHCID 82267Sulfamide

生成物 1

HCID 2767411-Piperidinesulfonamide

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

実験手順

Piperidine (3.0 g) and sulfamide (5.93 g) in 1,4-dioxane (100 ml) were heated at reflux for 24 h. The solvent was evaporated under reduced pressure and the resulting solid suspended in CHCl3. The suspension was filtered and the filtrate concentrated in vacuo to afford the subtitle compound as a white solid. Yield: 3.85 g.

後処理

  1. temperatureat reflux for 24 h
  2. customThe solvent was evaporated under reduced pressure
  3. filtrationThe suspension was filtered
  4. concentrationthe filtrate concentrated in vacuo

出典と根拠

ORDレコード
ord-ee0d5e1762a847a1929db3d27db38938
出典データセット
uspto-grants-2012_01
特許番号
US08106063B2

関連ノート

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