Piperidine → 1-Piperidinesulfonamide
反応式
[NH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[S:7](N)([NH2:10])(=[O:9])=[O:8]>O1CCOCC1>[N:1]1([S:7]([NH2:10])(=[O:9])=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1参加物
4
実験手順
Piperidine (3.0 g) and sulfamide (5.93 g) in 1,4-dioxane (100 ml) were heated at reflux for 24 h. The solvent was evaporated under reduced pressure and the resulting solid suspended in CHCl3. The suspension was filtered and the filtrate concentrated in vacuo to afford the subtitle compound as a white solid. Yield: 3.85 g.
後処理
- temperatureat reflux for 24 h
- customThe solvent was evaporated under reduced pressure
- filtrationThe suspension was filtered
- concentrationthe filtrate concentrated in vacuo
出典と根拠
- ORDレコード
- ord-ee0d5e1762a847a1929db3d27db38938
- 出典データセット
- uspto-grants-2012_01
- 特許番号
- US08106063B2
反応ノート
読み込み中…