化工社化工社 化学情報印刷レポート · 研究参考用
4-Phenylpiperidine → [(1R,2S)-1-Benzyl-2-hydroxy-3-(4-phenyl-piperidin-1-yl)-propyl]-carbamic acid tert-butyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Phenylpiperidine | HCID 69873 | — |
| 反応物 | erythro-N-Boc-D-phenylalanine epoxide | HCID 11357515 | — |
| 生成物 | [(1R,2S)-1-Benzyl-2-hydroxy-3-(4-phenyl-piperidin-1-yl)-propyl]-carbamic acid tert-butyl ester | HCID 66703612 | — |
反応手順
Using general procedure 1 and purification method E with [(1R)-1-{(2R)-oxiran-2-yl}-2-phenyl-ethyl]carbamic acid tert-butylester (0.10 g, 0.38 mmol) and 4-phenyl-piperidine (0.122 g, 0.76 mmol) gives the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08106090B2 |
| 出典データセット | uspto-grants-2012_01 |
| ORD ID | ord-54ea1127c618433295f4bf6725ef2980 |
| 出典メモ | uspto-grants-2012_01 |