Aluminum(III) Chloride → 1-(4-Chloro-2-hydroxyphenyl)ethanone
反応式
[OH:1][C:2]1[CH:7]=[C:6](OC(C(OCC)=O)(C)C)[CH:5]=[CH:4][C:3]=1[C:17](=[O:19])[CH3:18].[Cl-:20].[Al+3].[Cl-].[Cl-]>>[Cl:20][C:6]1[CH:5]=[CH:4][C:3]([C:17](=[O:19])[CH3:18])=[C:2]([OH:1])[CH:7]=1参加物
3
反応条件
- 温度
- 200 °C
実験手順
3-chlorophenyl acetate (starting material 2) was mixed with aluminium chloride (3 eq). The mixture was heated at 200° C. for 1 hour. The reaction medium was cooled. to room temperature then poured in ice. The aqueous phase was extracted with methylene chloride which was dried on magnesium sulfate then vacuum evaporated.
後処理
- temperatureThe reaction medium was cooled
- additionto room temperature then poured in ice
- extractionThe aqueous phase was extracted with methylene chloride which
- customwas dried on magnesium sulfate
- customvacuum evaporated
出典と根拠
- ORDレコード
- ord-d63a34b3f064470a8369c2b0156b97c1
- 出典データセット
- uspto-grants-2012_01
- 特許番号
- US08106097B2
反応ノート
読み込み中…