化工社化工社 化学情報印刷レポート · 研究参考用
Sesamol → 3-(4-chloro-5-fluoro-2-hydroxyphenyl)-3-hydroxy-1-pentyl-1,3-dihydro-2H-indol-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sesamol | HCID 68289 | — |
| 反応物 | 3-Chloro-4-fluorophenol | HCID 75790 | — |
| 反応物 | 1-Pentyl-1H-indole-2,3-dione | HCID 1581092 | — |
| 反応物 | 4-bromo-1-pentyl-1H-indole-2,3-dione | HCID 28492458 | — |
| 生成物 | 3-(4-chloro-5-fluoro-2-hydroxyphenyl)-3-hydroxy-1-pentyl-1,3-dihydro-2H-indol-2-one | HCID 58872497 | — |
反応手順
Following the procedure as described in PREPARATION 1C, and making non-critical variations to replace 4-bromo-1-pentyl-1H-indole-2,3-dione with 1-pentyl-1H-indole-2,3-dione, and 1,3-benzodioxol-5-ol with 3-chloro-4-fluorophenol, the title compound was obtained (14%): MS (ES+) m/z 346 (M−17), 386 (M+23).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08106087B2 |
| 出典データセット | uspto-grants-2012_01 |
| ORD ID | ord-7ea05cba03914eaa822c6655154cdf0a |
| 出典メモ | uspto-grants-2012_01 |