Benzoyl chloride → 1-Phenyl-2-(4-pyridyl)vinyl benzoate

反応式

[C:1]1([C:7](=[O:15])[CH2:8][C:9]2[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:16](Cl)(=[O:23])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[C:16]([O:15][C:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)=[CH:8][C:9]1[CH:10]=[CH:11][N:12]=[CH:13][CH:14]=1)(=[O:23])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

参加物

反応物 2

HCID 7412Benzoyl chloride

HCID 2871041-Phenyl-2-(4-pyridinyl)ethanone

生成物 1

HCID 684443451-Phenyl-2-(4-pyridyl)vinyl benzoate収率 62%

実験手順

Following a similar procedure to that described in reference example 4, but using 1-phenyl-2-(4-pyridyl)ethanone (obtained in reference example 3) instead of 1-(4-fluorophenyl)-2-(4-pyridyl)ethanone and benzoyl chloride instead of 4-fluorobenzoyl chloride, the title compound was obtained (yield: 62%).

出典と根拠

ORDレコード: ord-8d665b0c425a4fc6af6eba343ee489ec
出典データセット: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08536194B2

反応ノート

読み込み中…