化工社化工社 化学情報印刷レポート · 研究参考用
1-Bromopentane → 7-fluoro-{[5-(trifluoromethyl)-2-furyl]methyl}-1H-indole-2,3-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Bromopentane | HCID 8057 | — |
| 反応物 | 7-Fluoroisatin | HCID 586418 | — |
| 反応物 | 4-Bromoindole | HCID 676494 | — |
| 反応物 | 2-(Bromomethyl)-5-(trifluoromethyl)furan | HCID 2794605 | — |
| 生成物 | 7-fluoro-{[5-(trifluoromethyl)-2-furyl]methyl}-1H-indole-2,3-dione | HCID 66642570 | — |
反応手順
Following the procedure as described in PREPARATION 1A, and making tnon-critical variations to replace 4-bromoindole with 7-fluoroisatin, and 1-bromopentane with 2-(bromomethyl)-5-(trifluoromethyl)furan, the title compound was obtained (34%): MS (ES+) m/z 336.2 (M+23).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08106087B2 |
| 出典データセット | uspto-grants-2012_01 |
| ORD ID | ord-eeccaab0de1f4b48bffcc4d0c1e23b03 |
| 出典メモ | uspto-grants-2012_01 |