反応式
CN(C)[CH:3]=[C:4]([C:14]1[CH:19]=[CH:18][N:17]=[C:16]([S:20][CH3:21])[N:15]=1)[C:5]([C:7]1[CH:12]=[CH:11][C:10]([F:13])=[CH:9][CH:8]=1)=O.[O:23]=[C:24]([CH3:29])[CH2:25][C:26]([NH2:28])=[O:27]>>[F:13][C:10]1[CH:9]=[CH:8][C:7]([C:5]2[N:28]=[C:26]([OH:27])[C:25]([C:24](=[O:23])[CH3:29])=[CH:3][C:4]=2[C:14]2[CH:19]=[CH:18][N:17]=[C:16]([S:20][CH3:21])[N:15]=2)=[CH:12][CH:11]=1参加物
3
実験手順
Following a similar procedure to that described in reference example 10, but starting from 3-(dimethylamino)-1-(4-fluorophenyl)-2-[2-(methylsulfanyl)pyrimidin-4-yl]prop-2-en-1-one (obtained in reference example 20) and 3-oxobutyramide, the title compound was obtained.
出典と根拠
- ORDレコード
- ord-d3aae47ded0940a59aaa99693a98d066
- 出典データセット
- uspto-grants-2013_09
- 特許番号
- US08536194B2
関連ノート
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