関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Formamide | HCID 713 | — |
| 反応物 | 4-Aminobenzene-1,3-dioic acid | HCID 11355852 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | 4-Oxo-3,4-dihydroquinazoline-6-carboxylic acid | HCID 135703881 | 61% |
反応手順
A mixture of 4-amino isophthalic acid (17 g, 0.093 mol) and formamide (85 mL) was heated at 180° C. for 5 h. The reaction mixture was cooled to RT and added acetone. The solid precipitate thus obtained was stirred for 2 h, filtered and dried to give 4-oxo-3,4-dihydroquinazoline-6-carboxylic acid (11 g, 61%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08106214B2 |
|---|
| 出典データセット | uspto-grants-2012_01 |
|---|
| ORD ID | ord-298110cfea3646b4a00a3691ade77287 |
|---|
| 出典メモ | uspto-grants-2012_01 |
|---|
