化工社化工社 化学情報印刷レポート · 研究参考用
Pyridine → HCID 66703605、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Pyridine | HCID 1049 | — |
| 反応物 | 2-Fluoro-4-(trifluoromethyl)benzoyl chloride | HCID 145580 | — |
| 反応物 | 7-amino-1-methyl-3,4-dihydroquinolin-2(1H)-one | HCID 33699394 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | HCID 66703605 | HCID 66703605 | — |
反応手順
2-Fluoro-4-(trifluoromethyl)benzoyl chloride was added to a pyridine solution of 7-amino-1-methyl-3,4-dihydroquinolin-2(1H)-one, followed by stirring at room temperature for 12 hours. Water was added to the reaction liquid, followed by stirring for 30 minutes and then the precipitated crystals were collected by filtration to obtain 2-fluoro-N-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)-4-(trifluoromethyl)benzamide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08106190B2 |
| 出典データセット | uspto-grants-2012_01 |
| ORD ID | ord-37e90418f05547b9ae14e3e6437759f8 |
| 出典メモ | uspto-grants-2012_01 |