3-Iodo-1-propanol → 3-[4,6-Diphenyl-5-(4-pyridyl)pyrazolo[3,4-b]pyridin-1-yl]propan-1-ol

HRID 42600

反応式

HRID 42600 の反応式
[C:1]1([C:7]2[C:12]([C:13]3[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=3)=[C:11]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[N:10]=[C:9]3[NH:25][N:26]=[CH:27][C:8]=23)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.I[CH2:29][CH2:30][CH2:31][OH:32]>>[C:1]1([C:7]2[C:12]([C:13]3[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=3)=[C:11]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[N:10]=[C:9]3[N:25]([CH2:29][CH2:30][CH2:31][OH:32])[N:26]=[CH:27][C:8]=23)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

3

反応物 2

HCID 693903-Iodo-1-propanolHCID 670148534,6-diphenyl-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridine

生成物 1

HCID 670133893-[4,6-Diphenyl-5-(4-pyridyl)pyrazolo[3,4-b]pyridin-1-yl]propan-1-ol

実験手順

Following a similar procedure to that described in examples 6 and 7, but using 4,6-diphenyl-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridine (obtained in example 2) instead of 4,6-bis(4-fluorophenyl)-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridine and 3-iodopropanol instead of iodoethane, the title compounds were obtained.

出典と根拠

ORDレコード
ord-58b49b75daf74c8fba5ed2b33e216b15
出典データセット
uspto-grants-2013_09
特許番号
US08536194B2

関連ノート

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