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HRID 42621作成日：2026年10月25日

Nicotinoyl chloride → N-[2-[4,6-Bis(4-fluorophenyl)-5-(4-pyridyl)pyrazolo[3,4-b]pyridin-2-yl]ethyl]nicotinamide

https://huagongshe.com/reaction/42621

反応式

関与物質

役割名称HCID仕込み量
反応物Nicotinoyl chlorideHCID 82604—
反応物2-(2-Aminoethyl)-4,6-bis(4-fluorophenyl)-5-(4-pyridyl)pyrazolo[3,4-b]pyridineHCID 67013573—
生成物N-[2-[4,6-Bis(4-fluorophenyl)-5-(4-pyridyl)pyrazolo[3,4-b]pyridin-2-yl]ethyl]nicotinamideHCID 68443044—

反応手順

Following a similar procedure to that described in example 245, but starting from 2-(2-aminoethyl)-4,6-bis(4-fluorophenyl)-5-(4-pyridyl)pyrazolo[3,4-b]pyridine (obtained in example 90) and nicotinoyl chloride hydrichloride (obtained in section a), the title compound was obtained.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08536194B2
出典データセットuspto-grants-2013_09
ORD IDord-439100f92aaa42f8bbff90d066c8829a
出典メモuspto-grants-2013_09