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HRID 42624作成日：2026年10月26日

2-(3-Bromopropoxy)tetrahydro-2H-pyran → 6-(4-Fluorophenyl)-4-(2-furyl)-5-(4-pyridyl)-2-[3-(tetrahydropyran-2-yloxy)propyl]pyrazolo[3,4-b]pyridine

https://huagongshe.com/reaction/42624

反応式

関与物質

役割名称HCID仕込み量
反応物2-(3-Bromopropoxy)tetrahydro-2H-pyranHCID 2777988—
反応物6-(4-fluorophenyl)-4-(2-furyl)-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridineHCID 67014974—
生成物6-(4-Fluorophenyl)-4-(2-furyl)-5-(4-pyridyl)-2-[3-(tetrahydropyran-2-yloxy)propyl]pyrazolo[3,4-b]pyridineHCID 68444458—

反応手順

Following a similar procedure to that described in examples 6 and 7, but starting from 6-(4-fluorophenyl)-4-(2-furyl)-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridine (obtained in example 171) and 2-(3-bromopropoxy)tetrahydropyran, the desired compound was obtained.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08536194B2
出典データセットuspto-grants-2013_09
ORD IDord-8f37a0f7fc454d6eb93760b202ce5b41
出典メモuspto-grants-2013_09