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Water → 5,8-Difluoro-1,4-benzodioxane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 2-(2,3,6-Trifluorophenoxy)ethanol | HCID 2777944 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 5,8-Difluoro-1,4-benzodioxane | HCID 4464242 | — |
反応手順
2-(2,3,6-Trifluorophenoxy) ethanol (48.8 g, 0.254 mole) and 24 g of anhydrous potassium carbonate in 800 ml of dimethylformamide was refluxed for 20 hours and then poured into water. This was extracted with ether, washed with water, and dried to give 5,8-difluoro-1,4-benzodioxane.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04171359 |
| 出典データセット | uspto-grants-1979_10 |
| ORD ID | ord-f8ca3c9a2c7248d7b8e319529edd37db |
| 出典メモ | uspto-grants-1979_10 |