Aluminium lithium hydride → 2-(3,4-Methylenedioxyphenyl)ethyl 1-methycyclopropyl carbinol
反応式
[CH3:1][C:2]1([C:5]([CH:7]=[CH:8][C:9]2[CH:14]=[CH:13][C:12]3[O:15][CH2:16][O:17][C:11]=3[CH:10]=2)=[O:6])[CH2:4][CH2:3]1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[CH2:16]1[O:15][C:12]2[CH:13]=[CH:14][C:9]([CH2:8][CH2:7][CH:5]([C:2]3([CH3:1])[CH2:3][CH2:4]3)[OH:6])=[CH:10][C:11]=2[O:17]1参加物
3
実験手順
2-(3,4-Methylenedioxyphenyl)ethyl 1-methycyclopropyl carbinol [IV; Ar is 3,4-methylenedioxyphenyl, R is CH3 ] was prepared from 23.4 g. of 2-(3,4-methylenedioxyphenyl)vinyl 1-methylcyclopropyl ketone (Preparation A3) and 3.88 g. of lithium aluminum hydride according to the procedure described above in Preparation B1, affording 18.8 g., b.p. 120°-130° C. (0.003 mm.).
後処理
- customaffording 18.8 g
出典と根拠
- ORDレコード
- ord-e6f24ba73f2743e1a43bb32e2522ecd7
- 出典データセット
- uspto-grants-1979_10
- 特許番号
- US04171378
反応ノート
読み込み中…