2-Fluorophenylboronic acid → 5-(2-Fluorophenyl)-1,3-benzodioxole-4-carbaldehyde
反応式
Br[C:2]1[CH:10]=[CH:9][C:5]2[O:6][CH2:7][O:8][C:4]=2[C:3]=1[CH:11]=[O:12].[F:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1B(O)O>>[F:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[C:2]1[CH:10]=[CH:9][C:5]2[O:6][CH2:7][O:8][C:4]=2[C:3]=1[CH:11]=[O:12]参加物
3
実験手順
The process described in Method B was followed. 5-Bromo-1,3-benzodioxole-4-carbaldehyde (0.458 g, 2.00 mmol) and 2-fluorophenylboronic acid (0.420 g, 3.00 mmol) were used to obtain the title compound. The crude product was purified by column chromatography with a mixture of hexane:ethyl acetate (4:1) as the eluent.
出典と根拠
- ORDレコード
- ord-14ae1e7aee9c4c89b6c6bb11478e9e6a
- 出典データセット
- uspto-grants-2013_09
- 特許番号
- US08536210B2
反応ノート
読み込み中…