化工社化工社 化学情報印刷レポート · 研究参考用
Anthranilic Acid → 3,5-Dichlorobenzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Anthranilic Acid | HCID 227 | — |
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Isopropyl nitrite | HCID 10929 | — |
| 反応物 | Chlorine | HCID 24526 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 3,5-Dichlorobenzoic acid | HCID 5811 | 75% |
反応手順
137 parts of 2-aminobenzoic acid are introduced into 800 parts of ethanol, 50 parts of hydrochloric acid (20% strength of weight) and 500 parts of water. 163 parts of chlorine gas are passed in over 2 hours at 80° C. 300 parts of hydrochloric acid (36 percent strength by weight) are added. 125 parts of isopropyl nitrite are introduced in the course of 7 hours at 80° C. The mixture is cooled, 800 parts of water are added and the product is filtered off. 143 parts of 3,5-dichlorobenzoic acid (75% of theory) of melting point 173°-178° C. are obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04172098 |
| 出典データセット | uspto-grants-1979_10 |
| ORD ID | ord-e8f17bb12cf2427c8b7cde866133ee86 |
| 出典メモ | uspto-grants-1979_10 |