6-Chloro-5-formyl-1,3-dimethyluracil → 1,3-Dimethyl-6-(methylthio)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde

HRID 42696

反応式

HRID 42696 の反応式
Cl[C:2]1[N:7]([CH3:8])[C:6](=[O:9])[N:5]([CH3:10])[C:4](=[O:11])[C:3]=1[CH:12]=[O:13].[CH3:14][S-:15].[Na+]>>[CH3:8][N:7]1[C:2]([S:15][CH3:14])=[C:3]([CH:12]=[O:13])[C:4](=[O:11])[N:5]([CH3:10])[C:6]1=[O:9]

参加物

3

反応物 2

HCID 3199716-Chloro-5-formyl-1,3-dimethyluracilHCID 4378561Sodium methanethiolate

生成物 1

HCID 866586851,3-Dimethyl-6-(methylthio)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde

実験手順

The process described in Method D was followed. 6-Chloro-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde (0.404 g, 2.00 mmol) and sodium thiomethoxide (0.154 g, 2.20 mmol in 4 ml 1,4-dioxane) were used to obtain the title compound. The crude product was purified by washing with n-pentane.

出典と根拠

ORDレコード
ord-c7198cb84a3645cf8fbf9974ac7f14d0
出典データセット
uspto-grants-2013_09
特許番号
US08536210B2

関連ノート

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