(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal → Demannose

反応式

O=C[C@@H]([C@H]([C@@H](CO)O)O)O.[O:11]=[CH:12][C@@H:13]([C@H:15]([C@@H:17]([C@@H:19]([CH2:21][OH:22])[OH:20])[OH:18])[OH:16])[OH:14]>>[O:11]=[CH:12][C@H:13]([C@H:15]([C@@H:17]([C@@H:19]([CH2:21][OH:22])[OH:20])[OH:18])[OH:16])[OH:14]

参加物

反応物 2

HCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

HCID 644160aldehydo-D-Xylose

生成物 1

HCID 161658Demannose

反応条件

温度: 80 °C

実験手順

A mixture of 5.7 g (38.4 mmole) of D-xylose of mp. 153° C. and 6.9 g (38.4 mmole) of D-glucose of mp. 143° C. is heated to approximately 80° C. with 52.7 g (176.8 mmole) of BEPDIB. The readily volatile constituents are then removed in vacuo (10-3Torr). Subsequent distillation gives 7.3 g of bp. 78° C./10-3Torr in addition to 11 g of yellowish residue.

後処理

customThe readily volatile constituents are then removed in vacuo (10-3Torr)
distillationSubsequent distillation
customgives 7.3 g of bp. 78° C./10-3Torr

出典と根拠

ORDレコード: ord-a57f12c0dd8146639e6a128631e27211
出典データセット: uspto-grants-1979_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04172195

反応ノート

読み込み中…

参加物