関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | 3-Amino-4-chloro-2-methylthiomethylbenzotrifluoride | HCID 23352985 | — |
| 触媒 | Nickel | HCID 935 | — |
| 溶媒 | Potassium Hydroxide | HCID 14797 | — |
| 生成物 | Trifluoromethyl toluidine | HCID 2735932 | — |
反応手順
Dissolve 2 g. of 3-amino-4-chloro-2-methylthiomethylbenzotrifluoride in 50 ml. of 90% ethanol which is 1N in potassium hydroxide. Add 2 teaspoonsful of Raney nickel (W-2). Stir at 70° C. for 3 hours, cool and filter. Add 50 ml. of water and extract three times with hexane. Dry the combined organic extracts and evaporate to yield the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04172095 |
|---|
| 出典データセット | uspto-grants-1979_10 |
|---|
| ORD ID | ord-392def21d91848d499a8551560e39e13 |
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| 出典メモ | uspto-grants-1979_10 |
|---|
