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Phenylacetonitrile → HCID 178420213、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phenylacetonitrile | HCID 8794 | — |
| 反応物 | Ammonium azide | HCID 10313046 | — |
| 反応物 | (1-methyl-1H-tetrazol-5-yl)(phenyl)methanone | HCID 12331986 | — |
| 生成物 | HCID 178420213 | HCID 178420213 | — |
反応手順
Another process for the preparation of 5-benzoyl-1-methyltetrazole is known from J. Amer. Chem. Soc. 1963, 85, 2967-2976. Benzyl cyanide is reacted with ammonium azide to give 5-benzyltetrazole and then oxidized with chromium trioxide to give 5-benzoyltetrazole. The methylation to 5-benzoyl-1-methyltetrazole takes place with diazomethane. This synthesis route is likewise disadvantageous as regards safety and economical aspects.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08536211B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-8b07902def7e40a589fe52db19471ae8 |
| 出典メモ | uspto-grants-2013_09 |