1-Bromopropane → 3-(1,4-Dioxa-spiro[4,5]dec-8-yl)-5-cyano-1-n-propyl-indole
反応式
[O:1]1[C:5]2([CH2:10][CH2:9][CH:8]([C:11]3[C:19]4[C:14](=[CH:15][CH:16]=[C:17]([C:20]#[N:21])[CH:18]=4)[N:13]([CH2:22][CH3:23])[CH:12]=3)[CH2:7][CH2:6]2)[O:4][CH2:3][CH2:2]1.[CH2:24](Br)CC>>[O:4]1[C:5]2([CH2:10][CH2:9][CH:8]([C:11]3[C:19]4[C:14](=[CH:15][CH:16]=[C:17]([C:20]#[N:21])[CH:18]=4)[N:13]([CH2:22][CH2:23][CH3:24])[CH:12]=3)[CH2:7][CH2:6]2)[O:1][CH2:2][CH2:3]1参加物
3
実験手順
This compound was prepared in the manner described above for intermediate 5b by replacing ethylbromide with n-propylbromide (13.1 g, 11 mmol) to afford 4.33 g (75%) of the title compound as a oil: MS EI m/e 324 (M+)
後処理
- customThis compound was prepared in the manner
出典と根拠
- ORDレコード
- ord-e2aa1602be92486a8121b47e90352c4a
- 出典データセット
- uspto-grants-2001_11
- 特許番号
- US06313126B1
反応ノート
読み込み中…