化工社化工社 化学情報印刷レポート · 研究参考用
1,3-Dimethyl 2-(4-bromo-2-nitrophenyl)propanedioate → 4-Bromo-2-nitrophenylacetic Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,3-Dimethyl 2-(4-bromo-2-nitrophenyl)propanedioate | HCID 15740596 | — |
| 溶媒 | Hydrochloric Acid | HCID 313 | — |
| 生成物 | 4-Bromo-2-nitrophenylacetic Acid | HCID 271551 | 89% |
反応手順
Crude dimethyl 4-bromo-2-nitrophenylmalonate was heated at 110° C. in 40 mL of 6N hydrochloric acid for 24 hours and then cooled. The precipitate was collected by filtration, washed with water and dried to give 5.3 g (89% yield) of 4-bromo-2-nitrophenylacetic acid as an off white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06316429B1 |
| 出典データセット | uspto-grants-2001_11 |
| ORD ID | ord-7465f6374dc54cc780d29ecbb9ef2218 |
| 出典メモ | uspto-grants-2001_11 |