rel-(2R,6S)-2,6-Dimethylpiperidine → (2R,6S)-2,6-dimethyl-1-(3-{[4'-(1-pyrrolidinylcarbonyl)[1,1'-biphenyl]-4-yl]oxy}propyl)piperidine

関与物質

役割	名称	HCID	仕込み量
反応物	rel-(2R,6S)-2,6-Dimethylpiperidine	HCID 641768	—
反応物	[4'-(3-Chloropropoxy)[1,1'-biphenyl]-4-yl](pyrrolidin-1-yl)methanone	HCID 22994486	—
生成物	(2R,6S)-2,6-dimethyl-1-(3-{[4'-(1-pyrrolidinylcarbonyl)[1,1'-biphenyl]-4-yl]oxy}propyl)piperidine	HCID 70141065	—

The product from Example 11A and (2R,6S)-2,6-dimethylpiperidine were processed as described in Example 10F to provide the title compound.