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(4-Fluorophenyl)hydrazine → 5-Amino-1-(2,4-difluorophenyl)4-(6-quinolinoyl)-pyrazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (4-Fluorophenyl)hydrazine | HCID 69982 | — |
| 反応物 | (2,4-Difluoro-phenyl)-hydrazine | HCID 588958 | — |
| 反応物 | 3-Oxo-3-(quinolin-6-yl)propanenitrile | HCID 22262807 | — |
| 生成物 | 5-Amino-1-(2,4-difluorophenyl)4-(6-quinolinoyl)-pyrazole | HCID 22262817 | — |
反応手順
Proceeding as described in Example 1, step 2, but replacing 2-(3-bromobenzoyl)acetonitrile with 2-(6-quinolinoyl)acetonitrile and substituting 4-fluorophenylhydrazine in step 3 with 2,4-difluorophenylhydrazine was obtained 5-amino-1-(2,4-difluorophenyl)-4-(6-quinolinoyl)-pyrazole.HCl I 17) (mpt. 220-259.2).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06316466B1 |
| 出典データセット | uspto-grants-2001_11 |
| ORD ID | ord-34e09b9b35784eadab395a328453260f |
| 出典メモ | uspto-grants-2001_11 |