Acetic Acid → 3-Ethoxy-2-methylacrolein dimethylhydrazone

HRID 429512ノート

反応式

HRID 429512 の反応式
[CH2:1]([O:3][CH:4]=[C:5]([CH3:8])[CH:6]=O)[CH3:2].[CH3:9][N:10]([CH3:12])[NH2:11].C(O)(=O)C>C(OCC)C>[CH3:9][N:10]([CH3:12])[N:11]=[CH:6][C:5]([CH3:8])=[CH:4][O:3][CH2:1][CH3:2]

参加物

5

反応物 3

HCID 176Acetic AcidHCID 59761,1-DimethylhydrazineHCID 5591983-Ethoxy-2-methyl-2-propenal

生成物 1

HCID 541604213-Ethoxy-2-methylacrolein dimethylhydrazone

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

A mixture of 3-ethoxy-2-methyl-2-propenal, (E)- and (Z)- (4.0 g, 35 mmol), 1,1-dimethylhydrazine (2.73 g, 46 mmol) and acetic acid (0.04 g, 0.7 mmol) in diethyl ether is refluxed for one hour, cooled, washed sequentially with water and brine, dried over anhydrous magnesium sulfate, and concentrated in vacuo to give the title product as a yellow oil.

後処理

  1. temperaturecooled
  2. washwashed sequentially with water and brine
  3. dry with materialdried over anhydrous magnesium sulfate
  4. concentrationconcentrated in vacuo

出典と根拠

ORDレコード
ord-b6e0a9813e4e48e78850e44f9d941934
出典データセット
uspto-grants-2001_11
特許番号
US06316629B1

反応ノート

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