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tert-Butyl methyl ether → HCID 178435105、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | tert-Butyl methyl ether | HCID 15413 | — |
| 反応物 | 4,5-Dimethylthiazole | HCID 62510 | — |
| 反応物 | 2-Bromo-1-(thiophen-2-yl)ethan-1-one | HCID 2776372 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | HCID 178435105 | HCID 178435105 | — |
反応手順
A solution of 4,5-dimethylthiazole (2,2 g, 19.4 mmol) and 2-bromoacetylthiophene (4 g, 19.4 mmol) in ethyl alcohol (20 mL) was refluxed for 3 hours. It was cooled to room temperature and t-butyl methyl ether (10 mL) was added. The reaction mixture was left at room temperature overnight with stirring. The white product separated and was filtered and dried. It was crystallized from ethyl alcohol (4.42 g, 73%), m.p. 203-205° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06319934B1 |
| 出典データセット | uspto-grants-2001_11 |
| ORD ID | ord-07544ed515c34ce68a593ce274f675ff |
| 出典メモ | uspto-grants-2001_11 |