Water → 195532-64-0

HRID 430592ノート

反応式

HRID 430592 の反応式
[C:1]([C:3]1[C:4]([F:15])=[C:5]([CH:10]=[C:11]([F:14])[C:12]=1[F:13])[C:6]([O:8]C)=[O:7])#[N:2].O.S(=O)(=O)(O)O>C(O)(=O)C>[C:1]([C:3]1[C:4]([F:15])=[C:5]([CH:10]=[C:11]([F:14])[C:12]=1[F:13])[C:6]([OH:8])=[O:7])#[N:2]

参加物

5

反応物 3

HCID 962WaterHCID 1118Sulfuric AcidHCID 18417526Methyl 3-cyano-2,4,5-trifluoro-benzoate

生成物 1

HCID 18417533195532-64-0

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

A solution of 156 g of methyl 3-cyano-2,4,5-trifluoro-benzoate in a mixture of 960 ml of glacial acetic acid, 140 ml of water and 69 ml of concentrated sulphuric acid is heated to reflux for 8 hours. The acetic acid is distilled off and the resulting residue is treated with water. The precipitate is filtered off with suction, washed with water and dried.

後処理

  1. temperatureis heated
  2. temperatureto reflux for 8 hours
  3. distillationThe acetic acid is distilled off
  4. additionthe resulting residue is treated with water
  5. filtrationThe precipitate is filtered off with suction
  6. washwashed with water
  7. customdried

出典と根拠

ORDレコード
ord-0c03c2c2a7274f56b4f927e0c785bf43
出典データセット
uspto-grants-2001_11
特許番号
US06323213B1

反応ノート

読み込み中…