Hydrochloric Acid → HCID 15512465、化合物
反応式
Cl.[O:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[C:4]([CH2:11][CH2:12][N:13]2[CH2:18][CH2:17][CH:16]([NH:19]C(=O)OC(C)(C)C)[CH2:15][CH2:14]2)=[CH:3]1>C(O)C>[O:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[C:4]([CH2:11][CH2:12][N:13]2[CH2:14][CH2:15][CH:16]([NH2:19])[CH2:17][CH2:18]2)=[CH:3]1参加物
4
実験手順
235 ml of a 2.9N ethanolic hydrogen chloride solution are added to a solution of 21 g of the product obtained in Step A in 786 ml of ethanol. After 3 hours at 70° C. and then 16 hours at room temperature, the reaction mixture is concentrated under reduced pressure. The residue is taken up in 150 ml of water. The expected product is precipitated by the addition of 20% sodium hydroxide solution.
後処理
- concentration16 hours at room temperature, the reaction mixture is concentrated under reduced pressure
- customThe expected product is precipitated by the addition of 20% sodium hydroxide solution
出典と根拠
- ORDレコード
- ord-ee95cb936fe746b78fe524f2d7d4bea3
- 出典データセット
- uspto-grants-2001_11
- 特許番号
- US06323217B2
反応ノート
読み込み中…