関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 6-Aminonicotinic acid | HCID 18496 | — |
| 反応物 | 1-Methylpiperazine | HCID 53167 | — |
| 生成物 | (6-Aminopyridin-3-yl)(4-methylpiperazin-1-yl)methanone | HCID 57781845 | — |
反応手順
The title compound was prepared in analogy to the procedure described in Step 14.1 but using 6-amino-nicotinic acid and 1-methylpiperazine. The reaction mixture was stirred overnight at 0° C. DCM was used for dilution and extraction instead of EtOAc. The dried organic phase was concentrated to afford an impure sample of the title compound which was used without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08536175B2 |
|---|
| 出典データセット | uspto-grants-2013_09 |
|---|
| ORD ID | ord-65aef1e3c6b14e0c923194c276e06732 |
|---|
| 出典メモ | uspto-grants-2013_09 |
|---|
