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Potassium Carbonate → Benzimidazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 2-Chlorobenzimidazole | HCID 78572 | — |
| 反応物 | 2-Bromoacetyl-4-ethylthio-3-methylpyridine | HCID 14421553 | — |
| 生成物 | Benzimidazole | HCID 5798 | — |
反応手順
2-Chlorobenzimidazole is reacted with 2-bromoacetyl-4-ethylthio-3-methylpyridine in the presence of K2CO3 to give 2-chloro-1-[2-[4-ethylthio-3-methylpyridyl])-2-oxoethyl]benzimidazole. This is reacted with thiourea and treated with NH4OH to give 2-mercapto-1-(2-(2-(4-ethylthio-3-methylpyridyl))-2-oxoethyl)benzimidazole
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04725605 |
| 出典データセット | uspto-grants-1988_02 |
| ORD ID | ord-39008d9572cc46a1a61451fb05242526 |
| 出典メモ | uspto-grants-1988_02 |