化工社化工社 化学情報印刷レポート · 研究参考用
1-Acetylcyclohexene → 2-(1-Cyclohexenyl)-2-butanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Acetylcyclohexene | HCID 13612 | — |
| 反応物 | HCID 178418750 | HCID 178418750 | — |
| 生成物 | 2-(1-Cyclohexenyl)-2-butanol | HCID 10125081 | 56% |
反応手順
Diethylzinc addition to 1-(1-cyclohexenyl)-ethanone (1.04 mL, 8.05 mmol) was performed according to general procedure A using 2 mol % of Compound B enantiomer (88 mg). The product was purified by column chromatography (hexanes/EtOAc: 96/4) to give 697.1 mg of 9 (56% yield, 96% ee) of a colorless oil: [60 ]D 20=+5.9 (c 3.0, MeOH). [Published [α]D 20=+0.7 (c 3.0, MeOH, 51% ee)].
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06660884B2 |
| 出典データセット | uspto-grants-2003_12 |
| ORD ID | ord-e756d219a0af428290addef8bd61e8fc |
| 出典メモ | uspto-grants-2003_12 |