化工社化工社 化学情報印刷レポート · 研究参考用
2,3-Difluorophenol → 3,4-Bis(4-methoxyphenyl)-6-(2,3-difluorophenoxy)pyridazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,3-Difluorophenol | HCID 80879 | — |
| 反応物 | 3,4-Bis(4-methoxyphenyl)-6-chloropyridazine | HCID 12568084 | — |
| 生成物 | 3,4-Bis(4-methoxyphenyl)-6-(2,3-difluorophenoxy)pyridazine | HCID 10273629 | — |
反応手順
In a similar manner as in Example 2, 3,4-bis(4-methoxyphenyl)-6-chloropyridazine (180 mg, 0.551 mmol) and 2,3-difluorophenol were reacted as starting materials at 150° C. for 19 hours and post-treatment was then conducted, whereby the title compound was obtained as a colorless crystalline powder (203.3 mg, 90.0%). Melting point: 157.5-159.0° C. (chloroform-hexane).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06664256B1 |
| 出典データセット | uspto-grants-2003_12 |
| ORD ID | ord-b680130d5d8545f1a8890c75b8df9a63 |
| 出典メモ | uspto-grants-2003_12 |