Methanol → 5-(4-Methyl-4-nitropentyl)hydantoin

HRID 433004ノート

反応式

HRID 433004 の反応式
[CH3:1][C:2]([N+:14]([O-:16])=[O:15])([CH3:13])[CH2:3][CH2:4][CH:5]=[C:6]1[NH:10][C:9](=[O:11])[NH:8][C:7]1=[O:12].CO.[H][H]>[C].[Pd].O>[CH3:13][C:2]([N+:14]([O-:16])=[O:15])([CH3:1])[CH2:3][CH2:4][CH2:5][CH:6]1[NH:10][C:9](=[O:11])[NH:8][C:7]1=[O:12]

参加物

6

反応物 3

HCID 887MethanolHCID 695837495-(4-Methyl-4-nitropentylidene)hydantoinHCID 178418361HCID 178418361、化合物

生成物 1

HCID 99427025-(4-Methyl-4-nitropentyl)hydantoin収率 34.5%

試薬・触媒・溶媒 2

HCID 178418390HCID 178418390、化合物触媒2 回HCID 962Water溶媒

実験手順

To 5-(4-methyl-4-nitropentylidene)hydantoin (3.15 g, 13.9 mmol) were added methanol (60 ml) and water (10 ml), and the mixture was reduced by the addition of palladium-carbon (2.2 g) and hydrogen. After the reaction, palladium-carbon was filtered off and the residue was concentrated to dryness. Decantation with water and dichloromethane gave 5-(4-methyl-4-nitropentyl)hydantoin (1.1 g).

後処理

  1. filtrationwas filtered off
  2. concentrationthe residue was concentrated to dryness

出典と根拠

ORDレコード
ord-284c6a0603a3465db01ff65767ab23e7
出典データセット
uspto-grants-2003_12
特許番号
US06664412B2

反応ノート

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