4-Amino-3-[(propan-2-YL)amino]benzoic acid → 3-isopropyl-3H-benzotriazole-5-carboxylic acid
反応式
[NH2:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[NH:11][CH:12]([CH3:14])[CH3:13].[N:15]([O-])=O.[Na+]>Cl.O>[CH:12]([N:11]1[C:3]2[CH:4]=[C:5]([C:6]([OH:8])=[O:7])[CH:9]=[CH:10][C:2]=2[N:1]=[N:15]1)([CH3:14])[CH3:13]参加物
5
実験手順
To a stirred, cold (0° C.) mixture of 4-amino-3-isopropylamino-benzoic acid (11 g) in 120 mL of 6 N hydrochloric acid was added drop-wise a solution of 5.9 g of sodium nitrite in 40 mL of water. After 2 hours the solids were collected by filtration, washed with water, and dried to give 9 grams of 3-isopropyl-3H-benzotriazole-5-carboxylic acid.
後処理
- filtrationAfter 2 hours the solids were collected by filtration
- washwashed with water
- customdried
出典と根拠
- ORDレコード
- ord-abdfaec897864829b313177504c7942e
- 出典データセット
- uspto-grants-2003_12
- 特許番号
- US06664395B2
反応ノート
読み込み中…