(R)-(-)-1-Methyheptyl 4-Methoxycarbonyloxybenzoate → (R)-(-)-1-Methylheptyl 4-Hydroxybenzoate

HRID 433043ノート

反応式

HRID 433043 の反応式
COC([O:5][C:6]1[CH:22]=[CH:21][C:9]([C:10]([O:12][C@H:13]([CH3:20])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])=[O:11])=[CH:8][CH:7]=1)=O>C(O)C.N>[OH:5][C:6]1[CH:22]=[CH:21][C:9]([C:10]([O:12][C@H:13]([CH3:20])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])=[O:11])=[CH:8][CH:7]=1

参加物

4

反応物 1

HCID 70010659(R)-(-)-1-Methyheptyl 4-Methoxycarbonyloxybenzoate

生成物 1

HCID 13980124(R)-(-)-1-Methylheptyl 4-Hydroxybenzoate

試薬・触媒・溶媒 2

HCID 222Ammonia溶媒HCID 702Ethanol溶媒

実験手順

Compound 3 (11.6 g, 38 mmol) in ethanol (200 ml) and aqueous ammonia (50 ml) was stirred overnight. The solvents were removed in vacuo and the resulting colourless oil was purified by column chromatography (ethyl acetate) on silica.

後処理

  1. customThe solvents were removed in vacuo
  2. customthe resulting colourless oil was purified by column chromatography (ethyl acetate) on silica

出典と根拠

ORDレコード
ord-b0f16c51de7747f9ab721b7f67c9b915
出典データセット
uspto-grants-2003_12
特許番号
US06666989B1

反応ノート

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