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3,4-Difluoroaniline → 1-Boc-4-[(3,4-difluorophenyl)amino]-piperidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3,4-Difluoroaniline | HCID 77469 | — |
| 反応物 | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| 反応物 | tert-Butyl 4-(4-fluoroanilino)piperidine-1-carboxylate | HCID 16413902 | — |
| 生成物 | 1-Boc-4-[(3,4-difluorophenyl)amino]-piperidine | HCID 22558033 | — |
反応手順
The title compound was prepared from 1,1-dimethylethyl 4-oxo-1-piperidinecarboxylate and 3,4-difluoroaniline using a method similar to that described for D1 although the crude product was purified by chromatography.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08536182B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-3edec24171bf45e297a6b2f415193f29 |
| 出典メモ | uspto-grants-2013_09 |