3-Chlorophenylacetic acid → 2-[(3-Chlorophenyl)acetamido)butyric acid iso-butyl ester

HRID 433523

反応式

HRID 433523 の反応式
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:8][C:9]([OH:11])=O)[CH:5]=[CH:6][CH:7]=1.[NH2:12][CH:13]([CH2:21][CH3:22])[C:14]([O:16][CH2:17][CH:18]([CH3:20])[CH3:19])=[O:15]>>[CH2:17]([O:16][C:14](=[O:15])[CH:13]([NH:12][C:9](=[O:11])[CH2:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=1)[CH2:21][CH3:22])[CH:18]([CH3:19])[CH3:20]

参加物

3

反応物 2

HCID 158793-Chlorophenylacetic acidHCID 13743360Isobutyl 2-aminobutyrate

生成物 1

HCID 155476412-[(3-Chlorophenyl)acetamido)butyric acid iso-butyl ester

実験手順

Following General Procedure BI above and using 3-chlorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

後処理

  1. customThe reaction was monitored by tlc on silica gel and purification
  2. filtrationwas by filtration

出典と根拠

ORDレコード
ord-51b973b1b585456e9ce48a60645e5e21
出典データセット
uspto-grants-2003_12
特許番号
US06667305B1

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