3-Nitrophenylacetic acid → N-[(3-nitrophenyl)acetyl]methionine Ethyl Ester

HRID 433545ノート

反応式

HRID 433545 の反応式
[N+:1]([C:4]1[CH:5]=[C:6]([CH2:10][C:11]([OH:13])=O)[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2].Cl.[CH2:15]([O:17][C:18](=[O:25])[C@H:19]([CH2:21][CH2:22][S:23][CH3:24])[NH2:20])[CH3:16]>>[CH2:15]([O:17][C:18](=[O:25])[C@H:19]([CH2:21][CH2:22][S:23][CH3:24])[NH:20][C:11](=[O:13])[CH2:10][C:6]1[CH:7]=[CH:8][CH:9]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=1)[CH3:16]

参加物

3

反応物 2

HCID 158763-Nitrophenylacetic acidHCID 3083785Ethyl L-methionate hydrochloride

生成物 1

HCID 53910855N-[(3-nitrophenyl)acetyl]methionine Ethyl Ester

実験手順

Following General Procedure BG above and using 3-nitrophenylacetic acid (Aldrich) and methionine ethyl ester hydrochloride (Aldrich), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by recrystallization from butyl chloride.

後処理

  1. customThe reaction was monitored by tlc on silica gel and purification
  2. customwas by recrystallization from butyl chloride

出典と根拠

ORDレコード
ord-cec6c8e501494e678258d8a50aec8f85
出典データセット
uspto-grants-2003_12
特許番号
US06667305B1

反応ノート

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