Hydrochloric Acid → HCID 69734699、化合物
反応式
[CH2:1]([O:3][C:4](=[O:29])[CH:5]([NH:25][C:26](=[O:28])[CH3:27])[CH2:6][C:7]1[O:11][N:10]=[C:9]([CH:12]([NH:17]C(OC(C)(C)C)=O)[CH2:13][CH:14]([CH3:16])[CH3:15])[CH:8]=1)[CH3:2].[ClH:30]>O1CCOCC1>[ClH:30].[CH2:1]([O:3][C:4](=[O:29])[CH:5]([NH:25][C:26](=[O:28])[CH3:27])[CH2:6][C:7]1[O:11][N:10]=[C:9]([CH:12]([NH2:17])[CH2:13][CH:14]([CH3:15])[CH3:16])[CH:8]=1)[CH3:2]参加物
4
実験手順
2-Acetylamino-3-[3-(1-tert-butoxycarbonylamino-3-methyl-butyl)-isoxazol-5-yl]-propionic acid ethyl ester (7F) (5.95 g, 14.5 mmol) was stirred in 4N hydrochloric acid in dioxane (25 mL) at room temperature overnight. The product was concentrated and dried under high vacuum to give the title compound as a white solid (5.38 g, 100%). MS (CI) m/z 312.2 (M+1 for the free base).