Benzoyl Peroxide → 1-Chloro-4-(1-chloro-2-methylpropan-2-yl)benzene

反応式

[C:1]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].S(Cl)([Cl:15])(=O)=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>>[Cl:11][C:8]1[CH:7]=[CH:6][C:5]([C:1]([CH3:4])([CH3:2])[CH2:3][Cl:15])=[CH:10][CH:9]=1

参加物

反応物 3

HCID 7187Benzoyl Peroxide

HCID 24648Sulfuryl chloride

HCID 77594Benzene, 1-chloro-4-(1,1-dimethylethyl)-

生成物 1

HCID 155826481-Chloro-4-(1-chloro-2-methylpropan-2-yl)benzene収率 56.5%

反応条件

温度: 100 °C

実験手順

To 25 g of 4-tert-butylchlorobenzene synthesized in (1) above were added 20 g of sulfuryl chloride and a catalytic amount of benzoyl peroxide, and the temperature was elevated and the mixture was maintained at 100° C. for 1 hour. Then, the mixture was distilled under reduced pressure to give 17.0 g of 2-(4-chlorophenyl)-2-methyl-1-chloropropane (bp.: 121°-123° C./10 mmHg).