化工社化工社 化学情報印刷レポート · 研究参考用
Sulfuric Acid → 5-Methyl-4-(trifluoromethyl)-1H-imidazole-2-carbaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | 2-(dimethoxymethyl)-5-methyl-4-(trifluoromethyl)-1H-imidazole | HCID 67549218 | — |
| 生成物 | 5-Methyl-4-(trifluoromethyl)-1H-imidazole-2-carbaldehyde | HCID 86648481 | 7.9% |
反応手順
The same operation as in Example (33b) was performed using 2-(dimethoxymethyl)-5-methyl-4-(trifluoromethyl)-1H-imidazole obtained in Example (36b) (about 2.17 mmol) and 2 N sulfuric acid (15 mL), to obtain 30.5 mg of the title compound as a white solid (7.9%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08536197B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-498d4b21d8644dc78b259e89ae49cdf6 |
| 出典メモ | uspto-grants-2013_09 |