2-(dimethoxymethyl)-5-ethyl-4-(trifluoromethyl)-1H-imidazole → 5-Ethyl-4-(trifluoromethyl)-1H-imidazole-2-carbaldehyde
反応式
C[O:2][CH:3](OC)[C:4]1[NH:5][C:6]([CH2:13][CH3:14])=[C:7]([C:9]([F:12])([F:11])[F:10])[N:8]=1>S(=O)(=O)(O)O>[CH2:13]([C:6]1[NH:5][C:4]([CH:3]=[O:2])=[N:8][C:7]=1[C:9]([F:11])([F:12])[F:10])[CH3:14]参加物
3
実験手順
The same operation as in Example (33b) was performed using 2-(dimethoxymethyl)-5-ethyl-4-(trifluoromethyl)-1H-imidazole obtained in Example (39c) (about 4.09 mmol) and 2 N sulfuric acid (30 mL), to obtain 228.3 mg of the title compound as a white solid (29%).
出典と根拠
- ORDレコード
- ord-c2732bdc31d840f1a6f62f8d8476e4c5
- 出典データセット
- uspto-grants-2013_09
- 特許番号
- US08536197B2
反応ノート
読み込み中…