Hydrochloric Acid → p-Butoxybenzyl chloride

関与物質

反応手順

Hydrogen chloride gas is passed into a mixture of 9.6 g of paraformaldehyde and 40 ml of 37% aqueous hydrochloric acid up to the formation of a clear solution. Subsequently, a solution of 30 g of n-butyloxybenzene in 20 ml of benzene is added dropwise at 15°-20° and the reaction mixture stirred for 4 hours at this temperature. The organic phase is separated off, washed twice with 30 ml amounts of water, dried and distilled. After distilling off the benzene, there is obtained 27 g of 4-n-butyloxybenzyl chloride; b.p. 102°/1 m bar.

情報源と証拠