化工社化工社 化学情報印刷レポート · 研究参考用
Dimethylformamide → 3-Chloro-1-methyl-1,2-dihydroquinoxalin-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethylformamide | HCID 6228 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 1-Methyl-1,4-dihydro-2,3-quinoxalinedione | HCID 600627 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 3-Chloro-1-methyl-1,2-dihydroquinoxalin-2-one | HCID 1471088 | — |
反応手順
A mixture of 56.1 g. (0.32 m.) of 1,4-dihydro-1-methylquinoxalin-2,3-dione, 10 ml. of DMF, 50 ml. (0.67 m.) of thionyl chloride and 1 l. of toluene was refluxed for 1 hour, cooled, and stripped, finally under high vcuum to a crude dark solid, m.p. 124°-130° C. of sufficient purity to use in the next step.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04400382 |
| 出典データセット | uspto-grants-1983_08 |
| ORD ID | ord-c610f961c9004721890a672d1c4516c2 |
| 出典メモ | uspto-grants-1983_08 |