関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Ammonia | HCID 222 | — |
| 反応物 | 1H-1,2,4-Triazole | HCID 9257 | — |
| 反応物 | Hexamethyldisilazane | HCID 13838 | — |
| 触媒 | Saccharin | HCID 5143 | — |
| 生成物 | 1-Trimethylsilyl-1,2,4-triazole | HCID 87558 | 124.7% |
反応手順
23.4 ml (0.11 mole) of hexamethyldisilazane were added to a mixture consisting of 10.35 g (0.15 mole) of 1,2,4-triazole and 127 mg (0.75 mmole) of saccharin heated to 126° C. and evolution of ammonia started immediately. After refluxing for 30 minutes, the calculated amount of ammonia was evolved as determined by the method described in Example 1A. Vacuum distillation yielded 19.37 g (91.6%) of 1-trimethylsilyl-1,2,4-triazole boiling at 76.5°-78.0° C. at 12 mm Hg and nD 25=1.4592.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04400509 |
|---|
| 出典データセット | uspto-grants-1983_08 |
|---|
| ORD ID | ord-444c485f5de048b295ef616b6fd3e31c |
|---|
| 出典メモ | uspto-grants-1983_08 |
|---|
