関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Sodium Azide | HCID 33557 | — |
| 反応物 | Rifamycin S | HCID 6436726 | — |
| 溶媒 | 2-Pyrrolidone | HCID 12025 | — |
| 生成物 | 3-Aminorifamycin S | HCID 12889622 | 22.4% |
反応手順
14 g rifamycin S were dissolved in 70 ml pyrrolidone and added with 2.6 g sodium azide. The solution was heated at 60° C for 15 min., then at 80° C for further 15 min. The reaction mixture was then treated as in Example 3 to obtain 3.2 g 3-amino-rifamycin S identical to that described in Example 3.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04007169 |
|---|
| 出典データセット | uspto-grants-1977_02 |
|---|
| ORD ID | ord-0f6a61451eeb44de9f280479b78cbdbc |
|---|
| 出典メモ | uspto-grants-1977_02 |
|---|
