Cycloheptylamine → HCID 12671225、化合物
反応式
Cl[C:2]1[N:7]2[N:8]=[CH:9][N:10]=[C:6]2[N:5]=[C:4]([CH3:11])[C:3]=1[CH2:12][CH2:13]Cl.[CH:15]1([NH2:22])[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1.C(N(CC)CC)C>C(O)C>[CH:15]1([N:22]2[C:2]3[N:7]4[N:8]=[CH:9][N:10]=[C:6]4[N:5]=[C:4]([CH3:11])[C:3]=3[CH2:12][CH2:13]2)[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1参加物
5
実験手順
A mixture of 2g of 7-chloro-6-(2-chloroethyl)-5-methyl-s-triazolo[1,5-a]pyrimidine, 0.98g of cycloheptylamine, 3 ml of triethylamine and 20 ml of ethanol was stirred under reflux for 1.5 hours and treated thereafter as described in Example 5. The crystals thus obtained were crystallized from tetrahydrofuranisopropyl ether to give 1.4g of pale yellow needles of m.p. 197° - 198° C.
後処理
- temperatureunder reflux for 1.5 hours
- additiontreated
- customThe crystals thus obtained
- customwere crystallized from tetrahydrofuranisopropyl ether
出典と根拠
- ORDレコード
- ord-fbdc9e5e3c2e41deb9a093e49b0049d8
- 出典データセット
- uspto-grants-1977_02
- 特許番号
- US04007189
反応ノート
読み込み中…