Benzylamine → HCID 12671230、化合物
反応式
Cl[C:2]1[N:7]2[N:8]=[CH:9][N:10]=[C:6]2[N:5]=[C:4]([CH3:11])[C:3]=1[CH2:12][CH2:13]Cl.[CH2:15]([NH2:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.C(N(CC)CC)C>C(O)C>[CH2:15]([N:22]1[C:2]2[N:7]3[N:8]=[CH:9][N:10]=[C:6]3[N:5]=[C:4]([CH3:11])[C:3]=2[CH2:12][CH2:13]1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1参加物
5
実験手順
A mixture of 2g of 7-chloro-6-(2-chloroethyl)-5-methyl-s-triazolo[1,5-a]pyrimidine, 0.94g of benzylamine, 3 ml of triethylamine and 20 ml of ethanol was stirred under reflux for 1 hour. The reaction mixture was then concentrated under reduced pressure and the residue was washed with water. The crystals thus obtained were recrystallized from ethanol to give 1.4g of colorless prisms of m.p. 170.5° - 172° C.
後処理
- temperatureunder reflux for 1 hour
- concentrationThe reaction mixture was then concentrated under reduced pressure
- washthe residue was washed with water
- customThe crystals thus obtained
- customwere recrystallized from ethanol
出典と根拠
- ORDレコード
- ord-e55ff1854022439fb5b84cc4eb176cc5
- 出典データセット
- uspto-grants-1977_02
- 特許番号
- US04007189
反応ノート
読み込み中…