Methanesulfonic Acid → P-Toluic Acid

HRID 436313ノート

反応式

HRID 436313 の反応式
[C:1]1([CH3:19])[CH:6]=[CH:5][C:4]([C:7]([O:9]C(C2C=CC(C)=CC=2)=O)=[O:8])=[CH:3][CH:2]=1.CS(O)(=O)=O>[N+](C)([O-])=O>[C:1]1([CH3:19])[CH:6]=[CH:5][C:4]([C:7]([OH:9])=[O:8])=[CH:3][CH:2]=1

参加物

4

反応物 2

HCID 6395Methanesulfonic AcidHCID 1394134-Methylbenzoic acid anhydride

生成物 1

HCID 7470P-Toluic Acid収率 100%

試薬・触媒・溶媒 1

HCID 6375Nitromethane溶媒

実験手順

25.4 g (0.1 mole) of para-toluic anhydride was dissolved in 100 ml of warm nitromethane and then 9.6 g (0.1 mole) of methane sulfonic acid was added. The reaction mixture was stirred for 20 minutes and then filtered, giving 13.72 g (0.1 mole) of para-toluic acid precipitant. The reaction was quantitative, resulting in the para-toluic methane sulfonic anhydride dissolved in nitromethane.

後処理

  1. filtrationfiltered

出典と根拠

ORDレコード
ord-d8010dacc4c4427e9aee3d8eaf79fcba
出典データセット
uspto-grants-1977_02
特許番号
US04008271

反応ノート

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