化工社化工社 化学情報印刷レポート · 研究参考用
Ethylenediamine → 4-nitro-2-methyl-N-(beta-ureido-ethyl)aniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethylenediamine | HCID 3301 | — |
| 反応物 | Benzene, 1-chloro-2-methyl-4-nitro- | HCID 83315 | — |
| 反応物 | Potassio isocyanate | HCID 11051572 | — |
| 反応物 | N-(2-methyl-4-nitrophenyl)ethane-1,2-diamine hydrochloride | HCID 17336835 | — |
| 生成物 | 4-nitro-2-methyl-N-(beta-ureido-ethyl)aniline | HCID 21454196 | — |
反応手順
4-nitro-2-methyl-N-(β-aminoethyl) aniline monohydrochloride is obtained by reacting ethylene diamine with 2-chloro-5-nitro-toluene. This monohydrochloride is then reacted with potassium isocyanate to produce 4-nitro-2-methyl-N-(β-ureidoethyl) aniline, which is reduced with hydrazine and Raney's nickel to 4-amino-2-methyl-N-(β-ureidoethyl) aniline.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04008272 |
| 出典データセット | uspto-grants-1977_02 |
| ORD ID | ord-d9cb57c3fa2f41339e62a27c145c8718 |
| 出典メモ | uspto-grants-1977_02 |